Chili pepper fruit extract contains several components that have strong hyperaemic and rubefacient effects on the skin by increasing neuron-peptide release and directly stimulating local blood flow. Capsicum's main active components are capsaicinoids, representing between 0.1 % to 1.5 % of the dry fruit weight. The most important of these components is capsaicin (70 % of total) which chemically is the vanillylamide of an 8-methyl-(trans)-non-6-enoic acid.