Salicylic Acid, USP

Salicylic Acid, USP

Item No. AHA-SAAC-01
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Description
Description
Organic beta hydroxy acid (chemical name: 2-hydroxybenzoic acid), occurs naturally in various plants. Melting Point: 159°C (318°F).
Benefits
  • Can be used for skin peels, anti-dandruff products, and in products for oily, acneic and/or blemished skin
  • Ideal for making products that need higher concentrations of salicylic acid
Use
Typical use level 0.5-3%. Typically, it is added to the water phase of formulas but it is only slightly soluble in water. If used at concentrations higher than 2%, octyldodecanol or propylene glycol should be used as solvent. Salicylic acid can be added also in powder form to a finished cream or lotion without dissolving it first in water or another solvent.
Applications
Peels and exfoliant products. Anti-acne products (max. 2%). Anti-dandruff products (max 3%). Wart-removing products (max. concentration depends on type of plaster vehicle used).
CAS
69-72-7
INCI
Salicylic acid
composition
Salicylic acid
Purity Grade
USP grade
Appearance
Fine, white powder, odorless
pH Value
pH of saturated solution: 2.4
Solubility
Water: about 0.2% at 20oC, about 1.7% at 75oC (by adding about 5% of sodium phosphate or another neutral salt, solubility of salicylic acid in water is increased to about 1.8%). Alcohol (ethanol): about 14% in pure ethanol, about 0.5% in 20% ethanol. Propylene glycol: about 3-6%. Glycerin: about 1.6%. Octyldodecanol: about 15-20%
Preservation
Preservative-free
Storage
Store light-protected at a cool and dry place
Country of Origin
France
Raw Material Source
Sodium phenoxide and carbon dioxide.
Manufacture
Salicylic acid is prepared from dry sodium phenoxide in a stream of carbon dioxide. It is further purified by crystallizing the sodium salicylate from water at a temperature not exceeding 20 deg C.
Animal Testing
Not animal tested
GMO
GMO-free (does not contain plant-derived components)
Vegan
Does not contain animal-derived components
HS Code
2101110000
Precautions
Make sure that you measure the pH value after adding salicylic acid as it can lower the pH significantly. A pH of lower than 3.5 should be avoided as skin irritations can occur. To avoid excess peeling/irritation of the skin be careful when using salicylic acid together with abrasive soaps or cleansers, alcohol-containing products, or other topical acne or peeling products (e.g. benzoyl peroxide, resorcinol, sulfur, tretinoin), soaps or cosmetics that dry the skin.
Warning
Salicylic acid should be used with caution in patients with chronic renal (kidney) insufficiency, gastric ulcer, severe anemia, patients intolerant to salicylate or diabetes. Avoid prolonged and excessive use on large area of body or on broken or inflamed skin. Avoid contact with eyes, mouth or other mucous membrane. It should also be used with caution on extremities of patients with impaired peripheral circulation.
Regulatory Information
Salicylic acid is registered as OTC-drug with the FDA. This means that, if you want to sell products containing salicylic acid, your facility must be registered with the FDA and operate under cGMP guidelines.
Special Instructions
Make sure that you measure the pH value after adding salicylic acid as it can lower the pH significantly. A pH of lower than 3.5 should be avoided as skin irritations can occur. To avoid excess peeling/irritation of the skin be careful when using salicylic acid together with abrasive soaps or cleansers, alcohol-containing products, or other topical acne or peeling products (e.g. benzoyl peroxide, resorcinol, sulfur, tretinoin), soaps or cosmetics that dry the skin. Salicylic acid should be used with caution in patients with chronic renal (kidney) insufficiency, gastric ulcer, severe anemia, patients intolerant to salicylate or diabetes. Avoid prolonged and excessive use on large area of body or on broken or inflamed skin. Avoid contact with eyes, mouth or other mucous membrane. It should also be used with caution on extremities of patients with impaired peripheral circulation.